Meðal annars eru fyrrum félagar Ragnars Sigurðssonar komnir áfram. Þeir slóu út Partizani frá Albaníu.

Anderlecht fór létt með Sparta Praha og unnu þeir samtals 6-0. Youri Tielemans, Lukasz Teodorczyk og Michael Heylen sáu um mörkin.

Partizani (Albanía) 0 - 0 FK Krasnodar (Rússland) (Samtals 0-4)

Anderlecht (Belgía) 3 - 0 Slavia Prag (Tékkland) (Samtals 6-0)
1-0 Youri Tielemans ('22 , víti)
2-0 Lukasz Teodorczyk ('40 , víti)
3-0 Michael Heylen ('61 )

AZ (Holland) 0 - 0 Vojvodina (Serbía) (Samtals: 3-0)

BATE (Hvíta Rússland) 2 - 2 Astana (Kazakhstan) (Samtals: 2-4)
1-0 Mikhail Gordejchuk ('27 )
1-1 Nemanja Maksimovic ('50 )
1-2 Patrick Twumasi ('76 )
2-2 Igor Stasevich ('89 , víti)

Genk (Belgía) 2 - 0 NK Lokomotiva (Króatía) (Samtals 4-2)
1-0 Mbwana Samatta ('2 )
2-0 Leon Bailey ('50 )

Osmanlispor (Tyrkland) 2 - 0 Midtjylland (Danmörk (Samtals 3-0)
1-0 Tiago Pinto ('20 )
2-0 Tiago Pinto ('50 )

PAOK (Grikkland) 2 - 0 Dinamo Tb. (Georgia) (Samtals: 5-0)
1-0 Garry Mendes Rodrigues ('5 )
2-0 Giorgos Tzavellas ('45 )

Shkendija (Makedónía) 0 - 4 Gent (Belgía)
0-1 Kalifa Coulibaly ('60 )
0-2 Kalifa Coulibaly ('69 )
0-3 Jeremy Perbet ('81 )
0-4 Renato Neto ('86 )

Sparta Prag (Tékkland) 3 - 2 SönderjyskE (Danmörk) (Samtals 3-2)
0-1 Mikael Uhre ('35 )
0-2 Troels Klove ('40 )
1-2 David Lafata ('44 )
2-2 Josef Sural ('69 )
3-2 Jakub Brabec ('85 )